Class TSubstanceProteinSubunit

Unit

Declaration

type TSubstanceProteinSubunit = class(TBackboneElement)

Description

A SubstanceProtein is defined as a single unit of a linear amino acid sequence, or a combination of subunits that are either covalently linked or have a defined invariant stoichiometric relationship. This includes all synthetic, recombinant and purified SubstanceProteins of defined sequence, whether the use is therapeutic or prophylactic. This set of elements will be used to describe albumins, coagulation factors, cytokines, growth factors, peptide/SubstanceProtein hormones, enzymes, toxins, toxoids, recombinant vaccines, and immunomodulators.

Hierarchy

Overview

Methods

Public constructor Create; override;

Properties

Public property subunit : integer read Getsubunit write Setsubunit;
Public property subunitElement : Tinteger read GetsubunitElement write SetsubunitElement;
Public property sequence : string read Getsequence write Setsequence;
Public property sequenceElement : Tstring read GetsequenceElement write SetsequenceElement;
Public property length : integer read Getlength write Setlength;
Public property lengthElement : Tinteger read GetlengthElement write SetlengthElement;
Public property sequenceAttachment : TAttachment read GetsequenceAttachment write SetsequenceAttachment;
Public property nTerminalModificationId : TIdentifier read GetnTerminalModificationId write SetnTerminalModificationId;
Public property nTerminalModification : string read GetnTerminalModification write SetnTerminalModification;
Public property nTerminalModificationElement : Tstring read GetnTerminalModificationElement write SetnTerminalModificationElement;
Public property cTerminalModificationId : TIdentifier read GetcTerminalModificationId write SetcTerminalModificationId;
Public property cTerminalModification : string read GetcTerminalModification write SetcTerminalModification;
Public property cTerminalModificationElement : Tstring read GetcTerminalModificationElement write SetcTerminalModificationElement;

Description

Methods

Public constructor Create; override;
 

Properties

Public property subunit : integer read Getsubunit write Setsubunit;

Index of primary sequences of amino acids linked through peptide bonds in order of decreasing length. Sequences of the same length will be ordered by molecular weight. Subunits that have identical sequences will be repeated and have sequential subscripts.

Public property subunitElement : Tinteger read GetsubunitElement write SetsubunitElement;
 
Public property sequence : string read Getsequence write Setsequence;

The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence.

Public property sequenceElement : Tstring read GetsequenceElement write SetsequenceElement;
 
Public property length : integer read Getlength write Setlength;

Length of linear sequences of amino acids contained in the subunit.

Public property lengthElement : Tinteger read GetlengthElement write SetlengthElement;
 
Public property sequenceAttachment : TAttachment read GetsequenceAttachment write SetsequenceAttachment;

The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence.

Public property nTerminalModificationId : TIdentifier read GetnTerminalModificationId write SetnTerminalModificationId;

Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID.

Public property nTerminalModification : string read GetnTerminalModification write SetnTerminalModification;

The name of the fragment modified at the N-terminal of the SubstanceProtein shall be specified.

Public property nTerminalModificationElement : Tstring read GetnTerminalModificationElement write SetnTerminalModificationElement;
 
Public property cTerminalModificationId : TIdentifier read GetcTerminalModificationId write SetcTerminalModificationId;

Unique identifier for molecular fragment modification based on the ISO 11238 Substance ID.

Public property cTerminalModification : string read GetcTerminalModification write SetcTerminalModification;

The modification at the C-terminal shall be specified.

Public property cTerminalModificationElement : Tstring read GetcTerminalModificationElement write SetcTerminalModificationElement;
 

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